Zykadia (ceritinib) — Uses, Dosage, Side Effects & Safety

Drug class: Tyrosine kinase inhibitor (ALK inhibitor)

Overview

Zykadia is a prescription medicine used to treat adults with a specific type of lung cancer called non-small cell lung cancer (NSCLC) that is positive for an abnormal anaplastic lymphoma kinase (ALK) gene. It is typically used when the cancer has spread to other parts of the body (metastatic) and is either newly diagnosed or has progressed after other treatments. Zykadia works by blocking the activity of the ALK protein, which helps stop or slow the growth of cancer cells. It is taken by mouth, usually once daily, and should be taken with food to improve absorption and reduce stomach upset. Key points for patients: Zykadia can cause side effects such as nausea, diarrhea, and liver problems. Regular monitoring and communication with your healthcare provider are important to manage side effects and ensure the medicine is working effectively.

Frequently Asked Questions about Zykadia

What is Zykadia used for?

Zykadia is used to treat adults with ALK-positive metastatic non-small cell lung cancer (NSCLC).

How should I take Zykadia?

Take Zykadia once daily with food, at the same time each day. Swallow the tablets whole.

What are the most common side effects?

The most common side effects are diarrhea, nausea, vomiting, stomach pain, tiredness, and decreased appetite.

Can Zykadia cause liver problems?

Yes, Zykadia can cause serious liver problems. Your doctor will monitor your liver function with blood tests.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember unless it is less than 12 hours before your next dose. Do not double up doses.

Are there any foods or medicines I should avoid?

Avoid grapefruit and grapefruit juice, and tell your doctor about all other medicines you are taking to avoid interactions.

Is Zykadia safe during pregnancy or breastfeeding?

Zykadia may harm an unborn baby and is not recommended during pregnancy or breastfeeding. Use effective contraception during treatment and for at least 6 months after the last dose.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.