Dasatinib (dasatinib) — Uses, Dosage, Side Effects & Safety

Drug class: Tyrosine kinase inhibitor

Overview

Dasatinib is a prescription medication used to treat certain types of blood cancers, specifically Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) in adults and children. It is often used when other treatments have not worked or are not suitable. Dasatinib works by blocking specific proteins (tyrosine kinases) that promote the growth of cancer cells. By inhibiting these proteins, dasatinib helps slow or stop the spread of leukemia cells in the body. Key points for patients: Take dasatinib exactly as prescribed, usually once daily. It is important to have regular blood tests and medical check-ups while on this medication. Tell your doctor about any side effects or new symptoms, and avoid grapefruit products, which can interact with dasatinib.

Therapeutic uses

  • Chronic Myeloid Leukemia
  • Acute Lymphoblastic Leukemia

Common side effects

  • Myelosuppression
  • Fluid retention
  • Diarrhea
  • Headache
  • Pleural effusion
  • Hemorrhage
  • Cardiomyopathy

Frequently Asked Questions about Dasatinib

What is dasatinib used for?

Dasatinib is used to treat Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) in adults and children.

How does dasatinib work?

Dasatinib blocks specific proteins called tyrosine kinases, which are involved in the growth and spread of cancer cells. By inhibiting these proteins, it helps slow or stop the progression of leukemia.

Can I take dasatinib with food?

Yes, dasatinib can be taken with or without food. Take it at the same time each day for best results.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose. Do not double up.

Are there any foods or drinks I should avoid?

Avoid grapefruit and grapefruit juice, as they can increase dasatinib levels and risk of side effects.

Can I become pregnant or breastfeed while taking dasatinib?

No, dasatinib can harm an unborn baby. Use effective contraception during treatment and do not breastfeed while taking dasatinib.

What are the most serious side effects of dasatinib?

Serious side effects include severe bleeding, fluid retention (especially around the lungs), low blood cell counts, and pulmonary arterial hypertension. Seek immediate medical attention for severe symptoms.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.