Xospata (gilteritinib) — Uses, Dosage, Side Effects & Safety

Drug class: Tyrosine kinase inhibitor (FLT3 inhibitor)

Overview

Xospata is a prescription medicine used to treat adults with relapsed or refractory acute myeloid leukemia (AML) that has a specific genetic mutation called FLT3. It is only used after other treatments have not worked or the disease has returned. Xospata works by blocking the activity of the FLT3 protein, which is involved in the growth of cancer cells in certain types of AML. By targeting this protein, Xospata helps slow or stop the growth of leukemia cells. Patients should know that Xospata is taken by mouth as a tablet, usually once daily. Regular blood tests are needed to monitor for side effects and to check how well the medicine is working. Xospata can cause serious side effects, so it is important to follow your healthcare provider’s instructions closely.

Frequently Asked Questions about Xospata

What is Xospata used for?

Xospata is used to treat adults with relapsed or refractory acute myeloid leukemia (AML) that has a FLT3 mutation.

How does Xospata work?

Xospata blocks the FLT3 protein, which is involved in the growth of leukemia cells, helping to slow or stop the progression of AML.

What are the most common side effects of Xospata?

Common side effects include fatigue, nausea, diarrhea, constipation, cough, joint or muscle pain, swelling, and decreased appetite.

Can Xospata cause serious side effects?

Yes, Xospata can cause serious side effects such as differentiation syndrome, heart rhythm changes, liver problems, and increased risk of infections.

Is Xospata safe during pregnancy?

No, Xospata can harm an unborn baby. Effective contraception is required during treatment and for at least 6 months after the last dose.

What should I do if I miss a dose?

Take the missed dose as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose. Do not double up doses.

Can I take Xospata with other medications?

Some medications can interact with Xospata, especially those affecting liver enzymes or heart rhythm. Always inform your doctor about all medicines and supplements you are taking.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.