Sorafenib (sorafenib) — Uses, Dosage, Side Effects & Safety
Drug class: Multikinase inhibitor (antineoplastic agent)
Overview
Sorafenib is a prescription medicine used to treat certain types of cancer, including advanced kidney cancer (renal cell carcinoma), liver cancer (hepatocellular carcinoma), and thyroid cancer that cannot be treated with radioactive iodine. It works by blocking multiple proteins in cancer cells that help them grow and form new blood vessels, slowing or stopping the spread of cancer. Patients should know that sorafenib is taken by mouth as a tablet, usually twice daily. It is important to take it exactly as prescribed and not to stop without consulting your doctor. Common side effects include diarrhea, fatigue, and skin reactions. Regular monitoring by your healthcare provider is necessary to check for side effects and ensure the medication is working effectively.
Frequently Asked Questions about Sorafenib
What types of cancer does sorafenib treat?
Sorafenib is approved for advanced kidney cancer (renal cell carcinoma), liver cancer (hepatocellular carcinoma), and certain types of thyroid cancer that cannot be treated with radioactive iodine.
How long do I need to take sorafenib?
The duration of treatment depends on your response and tolerance to the medication. Your doctor will determine how long you should continue therapy.
Can I take sorafenib with food?
No, sorafenib should be taken on an empty stomach, at least 1 hour before or 2 hours after eating, to ensure proper absorption.
What should I do if I develop severe diarrhea or skin reactions?
Contact your healthcare provider immediately. Your doctor may adjust your dose or provide supportive care to manage these side effects.
Is it safe to use sorafenib during pregnancy?
No, sorafenib can harm an unborn baby. Use effective contraception during treatment and inform your doctor if you become pregnant.
Can I drink alcohol while taking sorafenib?
It is best to avoid alcohol, as it may increase the risk of liver problems and interact with your treatment.
Are there any routine tests needed while on sorafenib?
Yes, your doctor will monitor your blood pressure, liver function, kidney function, and blood counts regularly during treatment.
Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.