Radium 223 dichloride — Uses, Dosage, Side Effects & Safety
Drug class: Radiopharmaceutical, Antineoplastic Agent
Overview
Radium 223 dichloride is a prescription medicine used to treat adults with castration-resistant prostate cancer that has spread to bones but not to other organs. It is not a chemotherapy drug, but a targeted radiopharmaceutical therapy. Radium 223 works by mimicking calcium and binding to areas of increased bone turnover, delivering targeted radiation to bone metastases and helping to reduce pain and slow cancer progression. This medication is given by intravenous injection, usually in a hospital or clinic setting by a trained healthcare professional. Patients should be aware that regular blood tests are needed to monitor for side effects, especially effects on blood cell counts. It is important to attend all scheduled appointments and report any unusual symptoms to your doctor.
Therapeutic uses
- Treatment of castration-resistant prostate cancer
- Treatment of symptomatic bone metastases
- Treatment of prostate cancer with no known visceral metastatic disease
For related Radium 223 dichloride guidance, compare Yttrium and Xofigo.
Common side effects
- Myelosuppression
- Nausea
- Diarrhea
- Vomiting
- Peripheral edema
- Thrombocytopenia
- Anemia
Frequently Asked Questions about Radium 223 dichloride
What is Radium 223 dichloride used for?
Radium 223 dichloride is used to treat adults with castration-resistant prostate cancer that has spread to bones but not to other organs.
How does Radium 223 dichloride work?
It mimics calcium and targets bone metastases, delivering localized radiation to cancer cells in the bone while minimizing damage to surrounding healthy tissue.
What are the most common side effects?
Common side effects include nausea, diarrhea, vomiting, swelling, and mild decreases in blood cell counts.
Can women take Radium 223 dichloride?
No, it is not indicated for use in women, especially those who are pregnant or breastfeeding, due to potential harm to the fetus or infant.
How is Radium 223 dichloride administered?
It is given as an intravenous injection by a healthcare professional, usually every 4 weeks for 6 cycles.
What should I do if I miss a dose?
Contact your healthcare provider to reschedule your appointment. Do not attempt to self-administer the medication.
Are there any special precautions after receiving Radium 223 dichloride?
Yes, follow radiation safety instructions provided by your healthcare team, such as proper hygiene and limiting close contact with others for a short period after treatment.
Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.