Indinavir (Indinavir sulfate) — Uses, Dosage, Side Effects & Safety

Drug class: Infectious & Communicable Diseases

Overview

Indinavir is an antiretroviral medication used to treat human immunodeficiency virus (HIV) infection. It belongs to a class of drugs called protease inhibitors, which work by blocking the action of the HIV protease enzyme. This prevents the virus from multiplying and helps reduce the amount of HIV in the body. Indinavir is always used in combination with other antiretroviral medicines as part of highly active antiretroviral therapy (HAART). It does not cure HIV or acquired immunodeficiency syndrome (AIDS), but it helps improve immune function and lowers the risk of developing HIV-related complications. Key points for patients: Take indinavir exactly as prescribed, usually every 8 hours, and maintain good hydration to reduce the risk of kidney stones. Do not skip doses, and do not stop taking the medication without consulting your healthcare provider.

Therapeutic uses

• HIV-1 infection
• AIDS

For related Indinavir guidance, compare Lopinavir, Valganciclovir and Sofosbuvir/Ledipasvir.

Common side effects

• Nausea
• Vomiting
• Diarrhea
• Kidney stones
• Increased bilirubin
• Lipodystrophy
• Rash

Frequently Asked Questions about Indinavir

What is indinavir used for?

Indinavir is used in combination with other antiretroviral medications to treat HIV infection. It helps reduce the amount of HIV in the body and improves immune function, but it does not cure HIV or AIDS.

How should I take indinavir?

Take indinavir exactly as prescribed, usually every 8 hours on an empty stomach or with a light meal. Drink plenty of fluids to reduce the risk of kidney stones.

What are the most common side effects?

Common side effects include nausea, abdominal pain, headache, diarrhea, fatigue, and mild jaundice. Kidney stones can also occur.

Can indinavir be taken during pregnancy?

Indinavir should only be used during pregnancy if clearly needed and prescribed by a healthcare provider. Discuss risks and benefits with your doctor.

What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not double up doses.

Are there any foods or drinks I should avoid?

Avoid high-fat meals, as they can reduce absorption. Maintain good hydration and avoid alcohol to reduce the risk of liver and kidney problems.

Can indinavir cure HIV?

No, indinavir does not cure HIV. It helps control the virus and improve immune function when used as part of combination therapy.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.