Xerava (eravacycline) — Uses, Dosage, Side Effects & Safety

Drug class: Antibiotic (Tetracycline-class)

Overview

Xerava (eravacycline) is a broad-spectrum antibiotic used to treat complicated intra-abdominal infections in adults. It works by stopping the growth of bacteria, helping your body fight off serious infections in the stomach, intestines, and other abdominal organs. Xerava belongs to the tetracycline class of antibiotics, but it is specially designed to overcome resistance seen with older tetracyclines. It is only given by intravenous (IV) infusion in a hospital or clinical setting. Key points: Xerava is not effective against viral infections (such as colds or flu). It should only be used for infections proven or strongly suspected to be caused by susceptible bacteria. Always complete the full course as prescribed, even if you feel better.

Therapeutic uses

  • Complicated intra-abdominal infections (cIAI)
  • Hospital-acquired bacterial pneumonia (HABP)
  • Ventilator-associated bacterial pneumonia (VABP)

For related Xerava guidance, compare Omadacycline.

Common side effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Infusion site reactions
  • Abdominal pain
  • Elevated liver enzymes
  • Clostridioides difficile-associated diarrhea

Frequently Asked Questions about Xerava

What is Xerava used for?

Xerava is used to treat complicated intra-abdominal infections in adults, such as infections of the stomach, intestines, and other abdominal organs caused by susceptible bacteria.

How is Xerava given?

Xerava is administered as an intravenous (IV) infusion by a healthcare professional, typically every 12 hours.

Can Xerava be used in children?

No, Xerava is not approved for use in children under 18 years of age due to lack of safety and efficacy data.

What should I do if I miss a dose?

Contact your healthcare provider immediately. Do not attempt to self-administer or double the next dose.

Are there any foods or drinks to avoid while on Xerava?

There are no specific food or drink restrictions, but always follow your healthcare provider's instructions. Xerava is given by IV, so dietary interactions are minimal.

Can I take Xerava if I am pregnant or breastfeeding?

Xerava is not recommended during pregnancy or breastfeeding due to potential risks to the fetus or infant. Discuss alternatives with your doctor.

What are the most serious side effects of Xerava?

Serious side effects include severe allergic reactions, liver problems, and Clostridioides difficile-associated diarrhea. Seek immediate medical attention if you experience any of these.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.