Omadacycline — Uses, Dosage, Side Effects & Safety

Drug class: Antibiotic (Tetracycline-class)

Overview

Omadacycline is an antibiotic used to treat certain serious bacterial infections, including community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI) in adults. It belongs to the tetracycline class of antibiotics and works by stopping the growth of bacteria, helping your body fight off infection. Omadacycline is effective against a broad range of bacteria, including some that are resistant to other antibiotics. It is available as an oral tablet and as an intravenous (IV) injection, allowing for flexible treatment options. Key points for patients: Take Omadacycline exactly as prescribed, complete the full course even if you feel better, and let your healthcare provider know about any allergies or other medications you are taking. Do not use this medicine for viral infections like the common cold.

Therapeutic uses

  • Community-acquired bacterial pneumonia (CABP)
  • Acute bacterial skin and skin structure infections (ABSSSI)

For related Omadacycline guidance, compare Xerava.

Common side effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
  • Photosensitivity
  • Elevated liver enzymes
  • Clostridioides difficile-associated diarrhea

Frequently Asked Questions about Omadacycline

What infections does Omadacycline treat?

Omadacycline is used to treat community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI) in adults.

How should I take Omadacycline tablets?

Take Omadacycline tablets on an empty stomach, at least 4 hours after and 2 hours before any food, dairy, or antacids. Swallow the tablet whole with water.

Can I take Omadacycline if I am pregnant or breastfeeding?

Omadacycline is not recommended during pregnancy or breastfeeding unless clearly needed, due to potential risks to the baby.

What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

What are the most common side effects?

Common side effects include nausea, vomiting, diarrhea, headache, and infusion site reactions (for IV use).

Are there any foods or medicines I should avoid while taking Omadacycline?

Avoid antacids, calcium, magnesium, iron, and multivitamins within 4 hours of taking Omadacycline, as they can reduce its effectiveness.

Is Omadacycline safe for children?

Omadacycline is not recommended for use in children under 18 years, as safety and efficacy have not been established.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.