Nalmefene — Uses, Dosage, Side Effects & Safety

Drug class: Opioid receptor modulator (opioid antagonist)

Overview

Nalmefene is a medication used to help reduce alcohol consumption in adults with alcohol dependence who have a high drinking risk level. It works by blocking certain receptors in the brain (opioid receptors) that are involved in the rewarding effects of alcohol, helping to decrease the urge to drink. Nalmefene is typically prescribed as part of a comprehensive treatment program that includes counseling and psychosocial support. It is not intended for people who require immediate detoxification or for those with severe liver or kidney problems. Key points for patients: Nalmefene should be taken only when there is a perceived risk of drinking, and not every day. It is important to follow your healthcare provider’s instructions and attend regular follow-up appointments to monitor your progress.

Frequently Asked Questions about Nalmefene

What is nalmefene used for?

Nalmefene is used to help reduce alcohol consumption in adults with alcohol dependence who have a high drinking risk level. It is not a cure for alcoholism but can support efforts to reduce drinking.

How does nalmefene work?

Nalmefene works by blocking opioid receptors in the brain, which reduces the rewarding effects of alcohol and helps decrease the urge to drink.

Can I take nalmefene every day?

Nalmefene is intended to be taken only on days when you anticipate a risk of drinking, not every day. Follow your healthcare provider’s instructions.

Is nalmefene safe with other medications?

Nalmefene should not be used with opioid-containing medications. Always inform your healthcare provider about all medicines you are taking to avoid interactions.

What should I do if I experience side effects?

Mild side effects often improve with time. If you experience severe or persistent symptoms, contact your healthcare provider immediately.

Can nalmefene be used in pregnancy or breastfeeding?

Nalmefene is not recommended during pregnancy or breastfeeding unless the potential benefit outweighs the risk. Discuss with your doctor.

Is nalmefene available in Australia?

Yes, nalmefene is available in Australia under the brand name Selincro. It is listed on the Australian Register of Therapeutic Goods.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.