Jentadueto XR (linagliptin and metformin hydrochloride extended-release) — Uses, Dosage, Side Effects & Safety

Drug class: Antidiabetic agent (DPP-4 inhibitor and biguanide combination)

Overview

Jentadueto XR is a prescription medication used to help control blood sugar levels in adults with type 2 diabetes mellitus. It is a combination of two medicines: linagliptin, a DPP-4 inhibitor, and metformin, a biguanide. Together, they help your body manage blood glucose more effectively. Linagliptin works by increasing the levels of incretin hormones, which help the pancreas release more insulin and reduce the amount of sugar made by the liver. Metformin works mainly by decreasing glucose production in the liver and improving your body's sensitivity to insulin. Jentadueto XR is usually taken once daily with food to reduce stomach upset. It is not for use in people with type 1 diabetes or diabetic ketoacidosis. Regular monitoring of blood sugar and kidney function is important while taking this medication.

Therapeutic uses

  • Type 2 diabetes mellitus
  • Glycemic control improvement
  • Adjunct to diet and exercise for blood sugar management

For related Jentadueto XR guidance, compare Metformin in Canada, Metformin in France and Metformin in United States.

Common side effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Abdominal pain
  • Upper respiratory tract infection
  • Lactic acidosis
  • Pancreatitis
  • Hypoglycemia

Frequently Asked Questions about Jentadueto XR

What is Jentadueto XR used for?

Jentadueto XR is used to help control blood sugar levels in adults with type 2 diabetes, as part of a complete treatment plan including diet and exercise.

How should I take Jentadueto XR?

Take Jentadueto XR once daily with food, preferably with your evening meal. Swallow the tablet whole and do not crush or chew it.

What are the most common side effects?

The most common side effects are diarrhea, nausea, upset stomach, and headache. These are usually mild and temporary.

Can Jentadueto XR cause low blood sugar?

Jentadueto XR alone has a low risk of causing hypoglycemia, but the risk increases if taken with other diabetes medicines like insulin or sulfonylureas.

Is Jentadueto XR safe for people with kidney problems?

Jentadueto XR is not recommended for people with severe kidney impairment. Kidney function should be monitored before and during treatment.

What should I do if I miss a dose?

Take the missed dose as soon as you remember with food. If it's almost time for your next dose, skip the missed dose and continue your regular schedule. Do not double up.

Can I drink alcohol while taking Jentadueto XR?

Limit alcohol intake while taking Jentadueto XR, as alcohol increases the risk of lactic acidosis, a rare but serious side effect.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.