Hepatitis B vaccine (Hepatitis B vaccine (recombinant or plasma-derived)) — Uses, Dosage, Side Effects & Safety

Drug class: Vaccine (Inactivated Viral Vaccine)

Overview

The Hepatitis B vaccine is an immunization used to prevent infection caused by the hepatitis B virus (HBV), which can lead to serious liver diseases such as cirrhosis and liver cancer. It works by stimulating your immune system to produce antibodies that protect against the hepatitis B virus, without causing the disease itself. This vaccine is recommended for all infants, children, and adults who are at risk of HBV infection, including healthcare workers, people with chronic liver disease, and those traveling to areas where hepatitis B is common. The vaccine is given as a series of injections, usually in the upper arm muscle. Most people develop long-lasting immunity after completing the full vaccine series.

Therapeutic uses

  • Prevention of Hepatitis B infection
  • Prevention of chronic Hepatitis B infection
  • Prevention of liver cancer caused by Hepatitis B
  • Prevention of cirrhosis caused by Hepatitis B

For related Hepatitis B vaccine guidance, compare Hepatitis A vaccine.

Common side effects

  • Injection site pain
  • Fever
  • Headache
  • Fatigue
  • Nausea
  • Dizziness
  • Allergic reaction

Frequently Asked Questions about Hepatitis B vaccine

Who should get the Hepatitis B vaccine?

All infants, unvaccinated children, and adults at risk of hepatitis B infection (such as healthcare workers, people with chronic liver disease, and travelers to high-risk areas) should receive the vaccine.

How effective is the Hepatitis B vaccine?

The vaccine is highly effective, with over 90% of healthy individuals developing protective antibodies after completing the series.

Can I get hepatitis B from the vaccine?

No. The vaccine does not contain live virus and cannot cause hepatitis B infection.

Is the vaccine safe during pregnancy?

Yes, the Hepatitis B vaccine is considered safe during pregnancy and is recommended for pregnant women at risk of infection.

What should I do if I miss a dose?

Receive the missed dose as soon as possible. You do not need to restart the series; continue with the remaining doses as scheduled.

Are booster doses needed?

Booster doses are not routinely recommended for immunocompetent individuals, but may be considered for certain high-risk groups.

What are the signs of a serious allergic reaction?

Signs include difficulty breathing, swelling of the face or throat, rapid heartbeat, severe rash, or dizziness. Seek emergency medical attention if these occur.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.