Zidovudine (AZT) (zidovudine) — Uses, Dosage, Side Effects & Safety

Drug class: Antiretroviral (Nucleoside Reverse Transcriptase Inhibitor - NRTI)

Overview

Zidovudine (AZT) is an antiretroviral medication used to treat HIV infection and to help prevent the transmission of HIV from mother to child during childbirth. It is often used in combination with other antiretroviral drugs as part of highly active antiretroviral therapy (HAART) to reduce the amount of HIV in the body and improve immune function. Zidovudine works by blocking the action of reverse transcriptase, an enzyme that HIV needs to multiply. By interfering with this process, zidovudine helps slow the progression of HIV infection and reduces the risk of developing AIDS-related complications. Key points for patients: Zidovudine does not cure HIV or AIDS, but it helps manage the infection. It is important to take zidovudine exactly as prescribed, without missing doses, to maintain its effectiveness and reduce the risk of resistance.

For related Zidovudine (AZT) guidance, compare Videx (Didanosine.

Frequently Asked Questions about Zidovudine (AZT)

What is zidovudine (AZT) used for?

Zidovudine is used to treat HIV infection and to help prevent mother-to-child transmission of HIV during childbirth. It is always used in combination with other antiretroviral medications.

Can zidovudine cure HIV or AIDS?

No, zidovudine does not cure HIV or AIDS. It helps control the infection and improves immune function when used as part of combination therapy.

What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not double up doses.

What are the serious side effects of zidovudine?

Serious side effects include severe anemia, neutropenia, lactic acidosis, liver problems, and severe allergic reactions. Seek medical attention if you experience any of these.

Can zidovudine be used during pregnancy?

Yes, zidovudine is often used during pregnancy to reduce the risk of mother-to-child transmission of HIV. Your doctor will determine if it is appropriate for you.

Are there any foods or medicines I should avoid while taking zidovudine?

Avoid alcohol and medicines that can suppress bone marrow or affect the liver unless approved by your doctor. Always inform your healthcare provider of all medications you are taking.

How long do I need to take zidovudine?

You should take zidovudine for as long as your healthcare provider prescribes it. Do not stop without consulting your doctor, even if you feel well.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.