Vitamin K1 (phylloquinone (phylloquinone) — Uses, Dosage, Side Effects & Safety

Drug class: Vitamin, Fat-soluble; Hemostatic agent

Overview

Vitamin K1 (phylloquinone) is a fat-soluble vitamin essential for normal blood clotting. It is used to prevent and treat bleeding caused by low levels of vitamin K, including in newborns, people with vitamin K deficiency, and those taking anticoagulant medications like warfarin. Vitamin K1 works by helping your body produce clotting factors, which are proteins necessary for blood to clot and stop bleeding. It is commonly given by mouth or injection, depending on the urgency and severity of the deficiency. Key points: Vitamin K1 is safe when used as directed, but should only be used under medical supervision, especially in people with liver disease or those on blood thinners. It is also routinely given to newborns to prevent a rare but serious bleeding disorder.

Therapeutic uses

• Vitamin K deficiency
• Anticoagulant-induced prothrombin deficiency
• Hemorrhagic disease of the newborn
• Malabsorption syndromes (e.g., cystic fibrosis, celiac disease)

Common side effects

• Flushing
• Dizziness
• Rapid and weak pulse
• Sweating
• Low blood pressure
• Shortness of breath
• Cyanosis
• Allergic reactions (rash, itching, swelling)

Frequently Asked Questions about Vitamin K1 (phylloquinone

What is vitamin K1 used for?

Vitamin K1 is used to prevent and treat bleeding due to low vitamin K levels, reverse the effects of warfarin, and prevent vitamin K deficiency bleeding in newborns.

How is vitamin K1 given?

It can be taken by mouth as a tablet or solution, or given by injection (intravenous, intramuscular, or subcutaneous) by a healthcare professional.

Is vitamin K1 safe during pregnancy and breastfeeding?

Vitamin K1 is generally considered safe during pregnancy and breastfeeding when used as prescribed. Always consult your doctor before use.

Can vitamin K1 interact with other medications?

Yes, especially with blood thinners like warfarin, some antibiotics, and certain seizure medications. Always inform your healthcare provider about all medicines you take.

What should I do if I miss a dose?

Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double up doses.

What are signs of a serious reaction to vitamin K1?

Serious reactions include severe allergic symptoms (rash, swelling, trouble breathing), jaundice, or unusual bleeding. Seek immediate medical help if these occur.

Why do newborns receive vitamin K1?

Newborns receive vitamin K1 to prevent vitamin K deficiency bleeding, a rare but serious condition that can cause dangerous bleeding in infants.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.