Valbenazine (valbenazine) — Uses, Dosage, Side Effects & Safety

Drug class: Vesicular monoamine transporter 2 (VMAT2) inhibitor

Overview

Valbenazine is a prescription medication used to treat adults with tardive dyskinesia, a movement disorder characterized by uncontrollable, repetitive body movements, often caused by long-term use of certain psychiatric medications. It works by reducing abnormal movements through selective inhibition of the vesicular monoamine transporter 2 (VMAT2), which decreases the release of dopamine in specific areas of the brain. Patients taking valbenazine should know that it does not cure tardive dyskinesia but helps control symptoms. Improvement may be seen within a few weeks, but it is important to continue taking the medication as prescribed, even if symptoms improve. Regular follow-up with your healthcare provider is necessary to monitor for side effects and effectiveness.

Therapeutic uses

  • Tardive dyskinesia
  • Chorea associated with Huntington's disease

For related Valbenazine guidance, compare Tetrabenazine and Schizophrenia: Symptoms, Causes, and Evidence-Based Treatments.

Common side effects

  • Somnolence
  • Insomnia
  • Akathisia
  • Nausea
  • Dry mouth
  • Parkinsonism
  • QT prolongation

Frequently Asked Questions about Valbenazine

What is valbenazine used for?

Valbenazine is used to treat tardive dyskinesia, a movement disorder often caused by long-term use of antipsychotic medications.

How long does it take for valbenazine to work?

Some patients may notice improvement in abnormal movements within 2 weeks, but full benefits may take several weeks.

Can valbenazine cause drowsiness?

Yes, drowsiness or sleepiness is a common side effect. Avoid driving or operating machinery until you know how it affects you.

Is valbenazine safe during pregnancy or breastfeeding?

There is limited data on the use of valbenazine during pregnancy or breastfeeding. Discuss risks and benefits with your healthcare provider.

Can I stop taking valbenazine suddenly?

Do not stop taking valbenazine without consulting your doctor, as symptoms may return or worsen.

Are there any foods or drugs I should avoid while taking valbenazine?

Avoid alcohol and medications that are strong CYP3A4 inducers or MAOIs. Always inform your doctor about all medicines you are taking.

Is valbenazine available in Australia?

Yes, valbenazine is available in Australia under the brand name Ingrezza.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.