Urofollitropin (urofollitropin) — Uses, Dosage, Side Effects & Safety
Drug class: Gonadotropin (Follicle Stimulating Hormone, FSH)
Overview
Urofollitropin is a purified form of follicle-stimulating hormone (FSH) used to help women become pregnant by stimulating the ovaries to produce eggs. It is commonly prescribed as part of assisted reproductive technologies such as in vitro fertilization (IVF) or ovulation induction for women who do not ovulate regularly. This medication works by mimicking the natural FSH hormone in your body, encouraging the growth and development of ovarian follicles (which contain eggs). Urofollitropin is given by injection under the skin or into a muscle, usually under the supervision of a fertility specialist. Key points: Urofollitropin should only be used under close medical supervision, as it requires careful monitoring of your response to avoid complications such as ovarian hyperstimulation syndrome (OHSS). It is not effective in women with primary ovarian failure or in men for fertility purposes.
Therapeutic uses
- Induction of ovulation in women with polycystic ovary syndrome (PCOS) who have failed to ovulate with clomiphene citrate
- Development of multiple follicles in ovulatory women undergoing assisted reproductive technologies (ART) such as in vitro fertilization (IVF)
- Stimulation of spermatogenesis in men with hypogonadotropic hypogonadism who have previously received hCG therapy
Common side effects
- Abdominal pain
- Headache
- Ovarian hyperstimulation syndrome (OHSS)
- Injection site reactions
- Nausea
- Breast tenderness
- Ectopic pregnancy
- Multiple births
Frequently Asked Questions about Urofollitropin
What is urofollitropin used for?
Urofollitropin is used to stimulate the ovaries in women undergoing fertility treatments such as IVF or ovulation induction. It helps promote the growth of eggs in the ovaries.
How is urofollitropin administered?
It is given as an injection under the skin (subcutaneous) or into a muscle (intramuscular), usually once daily, as directed by your fertility specialist.
What are the main risks of urofollitropin?
The main risks include ovarian hyperstimulation syndrome (OHSS), multiple pregnancies, and allergic reactions. Close monitoring by your doctor is essential.
Can men use urofollitropin for infertility?
Urofollitropin is not typically used for male infertility. Other gonadotropins or hormonal therapies may be considered for men.
What should I do if I miss a dose?
Contact your healthcare provider for instructions. Do not double your next dose.
How will my doctor monitor my response to urofollitropin?
Your doctor will use blood tests and ultrasound scans to monitor your ovarian response and adjust your dose as needed.
Is urofollitropin safe during pregnancy?
Urofollitropin should not be used once pregnancy is confirmed. It is only used to help achieve pregnancy.
Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.