Umifenovir — Uses, Dosage, Side Effects & Safety

Drug class: Antiviral agent

Overview

Umifenovir is an antiviral medication primarily used to treat and prevent influenza and some other respiratory viral infections. It is not currently approved for use in the United States, Australia, or the United Kingdom, but is available in several other countries, including Russia, China, India, and Nepal. Umifenovir works by inhibiting the fusion of the virus with host cells, which helps prevent the virus from entering and multiplying in the body. This action can reduce the severity and duration of symptoms if taken early in the course of infection. Key points for patients: Umifenovir is most effective when started within 48 hours of symptom onset. It is generally well-tolerated, but should only be used under medical supervision. Always follow your healthcare provider's instructions regarding dosing and duration.

Therapeutic uses

  • Influenza
  • Acute respiratory viral infections
  • Coronaviruses (in vitro and some clinical studies)
  • Herpes simplex virus (in vitro)

For related Umifenovir guidance, compare Ribavirin, Common Cold vs. Flu (Influenza): Symptoms, Causes, and Treatment and High Cholesterol (Hypercholesterolemia): Causes, Symptoms, and Treatment.

Common side effects

  • Nausea
  • Diarrhea
  • Dizziness
  • Headache
  • Allergic reactions
  • Elevated liver enzymes

Frequently Asked Questions about Umifenovir

What is umifenovir used for?

Umifenovir is used to treat and prevent influenza and some other respiratory viral infections. It is not approved in the US, UK, or Australia, but is available in several other countries.

How does umifenovir work?

Umifenovir works by preventing viruses from entering human cells, thereby stopping their replication and spread.

Is umifenovir safe for children?

Umifenovir can be used in children over 2 years old, with dosing adjusted by weight and age. Always follow your healthcare provider's instructions.

Can I take umifenovir if I am pregnant or breastfeeding?

The safety of umifenovir in pregnancy and breastfeeding has not been fully established. Consult your doctor before use.

What should I do if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double up.

Are there any serious side effects I should watch for?

Serious side effects are rare but may include allergic reactions, jaundice, or severe abdominal pain. Seek immediate medical attention if these occur.

Can I use umifenovir with other antiviral medications?

Consult your healthcare provider before combining umifenovir with other antivirals, as interactions are possible.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.