Udenyca (pegfilgrastim-cbqv) — Uses, Dosage, Side Effects & Safety

Drug class: Colony Stimulating Factor (CSF); Hematopoietic Agent

Overview

Udenyca is a prescription medicine used to help reduce the risk of infection in people receiving certain types of chemotherapy that can lower white blood cell counts. It is a biosimilar to pegfilgrastim and works by stimulating your bone marrow to produce more neutrophils, a type of white blood cell important for fighting infections. Udenyca is given as a single injection under the skin, usually once per chemotherapy cycle. It helps your body recover faster from the effects of chemotherapy and lowers the risk of serious infections. Patients should be aware that while Udenyca reduces infection risk, it does not treat existing infections and should not be used in people with certain allergies. Key points: Udenyca is not a chemotherapy drug itself, but a supportive medication. It is important to follow your healthcare provider's instructions for timing and administration. Always report any signs of infection, such as fever or chills, to your doctor immediately.

Therapeutic uses

  • To decrease the incidence of infection, as manifested by febrile neutropenia, in patients with nonmyeloid malignancies receiving myelosuppressive anticancer drugs associated with a clinically significant incidence of febrile neutropenia.
  • To increase survival in patients acutely exposed to myelosuppressive doses of radiation (Hematopoietic Subsyndrome of Acute Radiation Syndrome [H-ARS]).

For related Udenyca guidance, compare Pegfilgrastim.

Common side effects

  • Bone pain
  • Nausea
  • Fatigue
  • Fever
  • Allergic reactions
  • Splenic rupture
  • Acute respiratory distress syndrome (ARDS)
  • Capillary leak syndrome

Frequently Asked Questions about Udenyca

What is Udenyca used for?

Udenyca is used to reduce the risk of infection in people receiving chemotherapy that can lower white blood cell counts by helping the body produce more neutrophils.

How is Udenyca administered?

Udenyca is given as a single subcutaneous injection, usually by a healthcare professional, 24 hours after chemotherapy.

What are the most common side effects of Udenyca?

Common side effects include bone pain, muscle aches, headache, and redness or swelling at the injection site.

Can I use Udenyca if I am pregnant or breastfeeding?

Inform your doctor if you are pregnant or breastfeeding. Udenyca should only be used if clearly needed and after discussing risks and benefits with your healthcare provider.

What should I do if I miss a dose?

Contact your healthcare provider for instructions. Do not take a double dose to make up for a missed injection.

Are there any serious risks with Udenyca?

Yes, serious risks include splenic rupture, severe allergic reactions, acute respiratory distress syndrome, and capillary leak syndrome. Seek immediate medical attention if you experience severe symptoms.

Is Udenyca a chemotherapy drug?

No, Udenyca is not a chemotherapy drug. It is a supportive medication used to help your body recover from the effects of chemotherapy.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.