Ublituximab — Uses, Dosage, Side Effects & Safety

Drug class: Monoclonal Antibody; Anti-CD20 Agent

Overview

Ublituximab is a prescription medication used to treat adults with relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease. It works by targeting a protein called CD20 found on the surface of certain immune cells (B cells), helping to reduce inflammation and prevent further damage to the nervous system. This medicine is given as an intravenous (IV) infusion by a healthcare professional, usually in a clinic or hospital setting. Ublituximab can help decrease the frequency of MS relapses and slow the progression of disability. Patients should be aware of possible infusion reactions and the risk of infections, and should discuss their full medical history with their healthcare provider before starting treatment.

Therapeutic uses

  • Relapsing forms of multiple sclerosis (RMS)
  • Clinically isolated syndrome (CIS)
  • Relapsing-remitting disease (RRMS)
  • Active secondary progressive disease (SPMS)

Common side effects

  • Infusion-related reactions
  • Infections
  • Headache
  • Diarrhea
  • Nausea
  • Neutropenia
  • Progressive multifocal leukoencephalopathy (PML)

Frequently Asked Questions about Ublituximab

What is ublituximab used for?

Ublituximab is used to treat adults with relapsing forms of multiple sclerosis (MS), helping to reduce relapses and slow disability progression.

How is ublituximab administered?

It is given as an intravenous (IV) infusion by a healthcare professional, typically in a clinic or hospital.

What are the most common side effects?

The most common side effects are infusion-related reactions (fever, chills, headache), upper respiratory infections, and fatigue.

Can I receive vaccines while on ublituximab?

You should not receive live vaccines during or after treatment with ublituximab. Discuss all vaccinations with your healthcare provider.

Is ublituximab safe during pregnancy or breastfeeding?

Ublituximab is not recommended during pregnancy or breastfeeding unless clearly needed. Discuss risks and benefits with your doctor.

What should I do if I miss a dose?

Contact your healthcare provider as soon as possible to reschedule your missed infusion. Do not try to make up the dose yourself.

Are there any serious risks with ublituximab?

Serious risks include severe infusion reactions, infections, and rare brain infections (PML). Report any unusual symptoms to your doctor immediately.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.