Travoprost
Pronunciation: (TRA-voe-prost).
- Generic name
- Travoprost
- Brand names
- Travoprost Ajanta, Travoprost Cipla, Travoprost Teva, Travoprost Sandoz, Travatan Z, Travatan
- Drug class
- Prostaglandin analog, Ophthalmic antiglaucoma agent
Availability and supply rules vary by country
Trade names by country: United States · Canada
Australia: · Full directory
What Travoprost is and how it works
Uses, formulations, monitoring, and supply rules can differ by patient, product, and country. Follow the exact local product information and professional advice.
Mechanism of action: how Travoprost works
Travoprost is a selective prostaglandin F2α analog that lowers intraocular pressure by increasing uveoscleral and trabecular outflow of aqueous humor from the eye. This reduces intraocular pressure, which is the main risk factor for glaucomatous optic nerve damage. (1)
What Travoprost is used for
Reduction of elevated intraocular pressure in patients with open-angle glaucoma
Reduction of elevated intraocular pressure in patients with open-angle glaucoma (1)
Reduction of elevated intraocular pressure in patients with ocular hypertension
Reduction of elevated intraocular pressure in patients with ocular hypertension (1)
Before taking Travoprost
Do not take / not appropriate for
- Contraindicated in patients with hypersensitivity to travoprost or any component of the formulation. (Contraindication) (1)
- Caution in pregnant or breastfeeding women. (Contraindication) (1)
Tell your clinician about
(1)How to take Travoprost
- General Instructions: Use Travoprost exactly as prescribed, usually one drop in the affected eye(s) once daily in the evening.. Adult Dosing: Instill one drop into the affected eye(s) once daily in the evening. Do not use more than once daily, as more frequent dosing may reduce effectiveness.. Pediatric Dosing: Safety and efficacy in children have not been established. Use only if prescribed by a pediatric ophthalmologist.. Administration: Wash hands before use. Tilt your head back, pull down the lower eyelid, and instill one drop. Close your eye and press gently on the inner corner for 1-2 minutes. Avoid touching the dropper tip to any surface.. When To Stop: Do not stop using Travoprost without consulting your doctor, even if you feel well. Stopping may cause increased eye pressure.. Storage: Store at room temperature (68–77°F/20–25°C). Protect from light. Keep the bottle tightly closed when not in use.
- This page does not provide a dose calculator. Dosing must follow the prescriber, pharmacist, or product label.
Procedures and treatment changes
Tell the treating team before surgery, procedures, or any medicine change. Do not alter treatment without the responsible clinician. (1)
Missed dose
If you miss a dose, use it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not use two doses at once.
Overdose
Overdose with Travoprost is unlikely with proper use. If accidental ingestion or excessive application occurs, rinse the eye(s) with water and seek medical attention if symptoms such as eye irritation, redness, or vision changes develop. (1)
Side effects
Side effects and their urgency vary; report severe, persistent, or concerning symptoms to a healthcare professional.
Ocular hyperemia
Incidence: Reported in the clinician-authored database; frequency not established
Eyelash changes
Incidence: Reported in the clinician-authored database; frequency not established
Iris pigmentation changes
Incidence: Reported in the clinician-authored database; frequency not established
Ocular pruritus
Incidence: Reported in the clinician-authored database; frequency not established
Dry eye
Incidence: Reported in the clinician-authored database; frequency not established
Blurred vision
Incidence: Reported in the clinician-authored database; frequency not established
Macular edema
Incidence: Reported in the clinician-authored database; frequency not established
Serious warnings
May cause gradual change in eye color (increased brown pigment in the iris) — serious
Symptoms: May cause gradual change in eye color (increased brown pigment in the iris). May increase eyelash length, thickness, and number. Use with caution in patients with a history of eye inflammation. Not recommended during pregnancy unless clearly needed. Remove contact lenses before use and wait at least 15 minutes before reinserting.
Action: Follow the urgency stated and seek prompt or emergency care when indicated. (1)
Contraindications recorded in the clinician database — serious
Symptoms: Contraindications recorded in the clinician database: Contraindicated in patients with hypersensitivity to travoprost or any component of the formulation. Use with caution in patients with active intraocular inflammation (e.g., uveitis), aphakia, or pseudophakia with a torn posterior lens capsule due to risk of macular edema. Caution in pregnant or breastfeeding women.
Action: Follow the urgency stated and seek prompt or emergency care when indicated. (1)
Interactions
| Medicine or test | Effect | Action |
|---|---|---|
| Recorded interactions | Travoprost is generally well tolerated with other ophthalmic medications, but using multiple prostaglandin analogs may reduce effectiveness. Inform your doctor about all eye drops and medications you use. No significant systemic drug interactions are reported. | (1) |
Pregnancy, breastfeeding, kidney/liver function, age
Pregnancy
In animal reproduction studies, travoprost given by injection to pregnant mice and rats throughout organogenesis caused embryo-fetal lethality, spontaneous abortion, and premature delivery at potentially clinically relevant doses. Because animal studies do not always predict the human response, the FDA label states travoprost should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus — discuss with the clinician managing your pregnancy. (1)
Breastfeeding
A study in lactating rats found that radiolabeled travoprost and/or its breakdown products were excreted in milk; it is not known whether travoprost or its metabolites pass into human breast milk. Because many drugs are excreted in human milk, the FDA label advises caution when travoprost is used by a nursing woman — discuss with the clinician managing your or your baby's care. (1)
Children
Frequency: Not applicable.. Weight Based: Not recommended for pediatric use.. Max Daily Dose: Not applicable.. Max Single Dose: Not applicable.. Age Restrictions: Safety and efficacy not established in children. (1)
Renal_impairment
The FDA label states travoprost has been studied in people with liver impairment and in people with kidney impairment, and no clinically meaningful changes in blood or urine laboratory tests were seen in either group — consistent with the very small amount of the eye-drop medicine that reaches the bloodstream. No specific dose adjustment is given for kidney or liver disease. Tell the prescribing clinician about any significant kidney or liver condition regardless, since this reflects laboratory monitoring in the studies, not a guarantee of safety in every individual case. (1)
Hepatic_impairment
The FDA label states travoprost has been studied in people with liver impairment and in people with kidney impairment, and no clinically meaningful changes in blood or urine laboratory tests were seen in either group — consistent with the very small amount of the eye-drop medicine that reaches the bloodstream. No specific dose adjustment is given for kidney or liver disease. Tell the prescribing clinician about any significant kidney or liver condition regardless, since this reflects laboratory monitoring in the studies, not a guarantee of safety in every individual case. (1)
Monitoring
(1)Storage
Store at 2°C to 25°C (36°F to 77°F). After opening, the bottle can be used until the expiration date printed on it. Protect from light and keep tightly closed when not in use.
Professional information
Clinician-facing context only. This section does not replace current product labeling.
General
Indication: Reduction of elevated intraocular pressure in patients with open-angle glaucoma
Dose summary: One drop in the affected eye(s) once daily in the evening.
Renal context: The FDA label states travoprost ophthalmic solution has been studied in patients with hepatic impairment and in patients with renal impairment, and no clinically relevant changes in hematology, blood chemistry, or urinalysis laboratory data were observed in these patients. No dose adjustment is specified for either renal or hepatic impairment, consistent with the drug's minimal systemic absorption as a topical eye drop. (1)
Frequently asked questions
How long does it take for Travoprost to lower eye pressure?
Travoprost typically begins to lower intraocular pressure within 2 to 4 hours after application, with maximum effect reached after 12 hours. Continued daily use is necessary for ongoing control.
Can Travoprost change my eye color?
Yes, Travoprost may cause gradual, permanent darkening of the iris (eye color), especially in people with mixed-color irises. This change may not be noticeable for months or years.
Is Travoprost safe during pregnancy or breastfeeding?
Travoprost should be used during pregnancy only if clearly needed and prescribed by your doctor. It is not known if Travoprost passes into breast milk. Discuss risks and benefits with your healthcare provider.
Can I use Travoprost with contact lenses?
Remove contact lenses before using Travoprost. Wait at least 15 minutes after applying the drops before reinserting your lenses.
What should I do if I accidentally get more than one drop in my eye?
If you accidentally use more than one drop, rinse your eye with water if irritation occurs. Resume your regular dosing schedule at the next dose. Do not use extra drops to make up for missed doses.
Are there any foods or activities I should avoid while using Travoprost?
There are no specific food restrictions. Avoid activities that require clear vision if you experience blurred vision after using the drops.
Can Travoprost be used in both eyes?
Yes, if prescribed for both eyes, use one drop in each affected eye as directed by your doctor.
What happens if I take too much Travoprost?
If an overdose of Travoprost eye drops occurs, it is unlikely to cause systemic toxicity due to the small amount of medication in each drop. However, excessive application may lead to increased local side effects such as eye irritation or redness. If you suspect an overdose or experience unusual symptoms, it is important to seek emergency medical attention immediately.
Can I drink alcohol while taking Travoprost?
There are no known direct interactions between Travoprost and alcohol. However, alcohol consumption can sometimes lead to dehydration, which may indirectly affect eye health. While moderate alcohol intake is generally not contraindicated, it is always advisable to discuss your alcohol consumption habits with your healthcare provider to ensure it does not interfere with your treatment or overall health.
Is Travoprost safe during pregnancy?
Travoprost is categorized as a Pregnancy Category C medication. This means that animal reproduction studies have shown an adverse effect on the fetus, but there are no adequate and well-controlled studies in humans. Therefore, Travoprost should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus. Always consult your doctor before using Travoprost if you are pregnant or planning to become pregnant.
What is the mechanism of action of Travoprost?
Travoprost is a selective prostaglandin F2α analog that lowers intraocular pressure by increasing uveoscleral and trabecular outflow of aqueous humor from the eye. This reduces intraocular pressure, which is the main risk factor for glaucomatous optic nerve damage. (1)
What is the generic name of Travoprost?
The generic name is Travoprost. It is sold under brand names including Travoprost Ajanta, Travoprost Cipla, Travoprost Teva, Travoprost Sandoz, Travatan Z, Travatan.
What class of drug is Travoprost?
Travoprost is classed as: Prostaglandin analog, Ophthalmic antiglaucoma agent.
References
- nullnull · null · accessed null · source 1
- TRAVOPROST OPHTHALMIC (TRAVOPROST OPHTHALMIC SOLUTION) SOLUTION [BRYANT RANCH PREPACK] — US prescribing information (DailyMed SPL)U.S. National Library of Medicine (DailyMed) · US · accessed 2026-08-14 · source 2
- Travoprost Ophthalmic — patient drug information (MedlinePlus)U.S. National Library of Medicine (MedlinePlus) · US · accessed 2026-08-14 · source 3
- Travoprost Ophthalmic Solution, 0.004% — FDA approval record (Drugs@FDA ANDA205050)U.S. Food and Drug Administration · US · accessed 2026-08-14 · source 4
- Travoprost — RxNorm normalized drug concept (RXCUI 283809)U.S. National Library of Medicine (RxNorm) · US · accessed 2026-08-14 · source 5
Brand names by country
Single-ingredient Travoprost names are shown separately by country. Product availability, strengths, and supply rules can change; combination products are not included here.
Priority countries
United States
- Travatan Z.04 mg/mL · novartis pharmaceuticals corporation
- iDose TR75 ug · glaukos corporation
- Travoprost Ophthalmic Soluton.04 mg/mL · sagent pharmaceuticals
Canada
- TRAVATAN Z
- IZBA
- TEVA-TRAVOPROST Z
- APO-TRAVOPROST Z