Tesamorelin — Uses, Dosage, Side Effects & Safety

Drug class: Growth Hormone-Releasing Hormone (GHRH) Analog

Overview

Tesamorelin is a prescription medication used to reduce excess abdominal fat (visceral adiposity) in adults with HIV-associated lipodystrophy. Lipodystrophy is a condition where abnormal fat distribution occurs, often as a side effect of certain HIV treatments. Tesamorelin works by mimicking a natural hormone in your body called growth hormone-releasing hormone (GHRH). This stimulates your pituitary gland to release more growth hormone, which helps break down fat stored in the abdomen. Key points for patients: Tesamorelin is not a weight loss drug for general obesity. It is specifically approved for HIV-related changes in body fat. It is given as a daily injection under the skin, and regular monitoring is important to check for side effects and effectiveness.

Therapeutic uses

  • Reduction of excess abdominal fat in HIV-infected patients with lipodystrophy
  • Improvement of body composition in HIV-infected patients with lipodystrophy

Common side effects

  • Injection site reactions
  • Hypersensitivity reactions
  • Arthralgia
  • Myalgia
  • Peripheral edema
  • Glucose intolerance
  • Antibody formation

Frequently Asked Questions about Tesamorelin

What is Tesamorelin used for?

Tesamorelin is used to reduce excess abdominal fat in adults with HIV-associated lipodystrophy. It is not approved for general weight loss or obesity.

How does Tesamorelin work?

Tesamorelin mimics a natural hormone (GHRH) to stimulate the release of growth hormone, which helps reduce visceral (abdominal) fat.

What are the common side effects of Tesamorelin?

Common side effects include injection site reactions, muscle pain, swelling, and joint pain.

Can Tesamorelin be used in children?

No, Tesamorelin is not approved for use in children or adolescents under 18 years of age.

Is Tesamorelin safe during pregnancy?

Tesamorelin should not be used during pregnancy. Inform your healthcare provider if you are pregnant or planning to become pregnant.

How should I store Tesamorelin?

Store unopened vials in the refrigerator. Protect from light and use reconstituted solution immediately or as directed.

What should I do if I miss a dose?

Take the missed dose as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose. Do not double up doses.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.