Streptomycin (streptomycin) — Uses, Dosage, Side Effects & Safety

Drug class: Aminoglycoside antibiotic

Overview

Streptomycin is an antibiotic used primarily to treat serious bacterial infections, including tuberculosis (TB), plague, tularemia, and certain other infections caused by susceptible bacteria. It is often used in combination with other antibiotics to prevent the development of resistance and to improve treatment outcomes. Streptomycin works by stopping the growth of bacteria. It does this by interfering with the bacteria's ability to make proteins, which are essential for their survival. This action helps your body fight off the infection more effectively. Key points for patients: Streptomycin is usually given as an injection by a healthcare professional. It is important to complete the full course of treatment, even if you start to feel better, to ensure the infection is fully cleared. Let your doctor know if you have any hearing problems, kidney issues, or if you are pregnant or breastfeeding.

Therapeutic uses

• Tuberculosis
• Plague
• Tularemia
• Brucellosis
• Bacterial endocarditis (in combination with penicillin)

For related Streptomycin guidance, compare Kanamycin, Amikacin and Rheumatoid Arthritis (RA): A Comprehensive Guide to Symptoms, Causes, and Treatment.

Common side effects

• Ototoxicity (hearing loss, vertigo)
• Nephrotoxicity (kidney damage)
• Neuromuscular blockade (muscle weakness, respiratory depression)
• Rash
• Fever
• Nausea
• Vomiting

Frequently Asked Questions about Streptomycin

What infections does streptomycin treat?

Streptomycin is used to treat tuberculosis, plague, tularemia, and other serious infections caused by susceptible bacteria. It is often used in combination with other antibiotics.

How is streptomycin given?

Streptomycin is given as an intramuscular injection, usually by a healthcare professional.

Can streptomycin cause hearing loss?

Yes, streptomycin can cause permanent hearing loss (ototoxicity), especially with prolonged use or high doses. Hearing should be monitored during treatment.

Is streptomycin safe in pregnancy?

Streptomycin should be used in pregnancy only if clearly needed, as it may cause harm to the fetus, including hearing loss. Discuss risks and benefits with your doctor.

What should I do if I miss a dose?

Contact your healthcare provider as soon as possible. Do not double the next dose.

What are the signs of serious side effects?

Serious side effects include hearing loss, severe dizziness, muscle weakness, decreased urination, and allergic reactions. Seek medical help immediately if these occur.

Can I take other antibiotics with streptomycin?

Streptomycin is often used with other antibiotics, but always inform your doctor about all medications you are taking to avoid harmful interactions.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.