Streptokinase (streptokinase) — Uses, Dosage, Side Effects & Safety

Drug class: Thrombolytic agent (fibrinolytic)

Overview

Streptokinase is a medication used to dissolve blood clots in the body. It is most commonly administered in hospitals to treat acute myocardial infarction (heart attack), pulmonary embolism, and deep vein thrombosis. By breaking down clots, it helps restore normal blood flow to affected tissues and organs. Streptokinase works by activating the body's natural clot-dissolving system. It converts plasminogen to plasmin, an enzyme that breaks down fibrin, the main component of blood clots. This action helps dissolve existing clots and can be life-saving in emergencies like heart attacks or severe lung clots. Patients should know that streptokinase is only given by healthcare professionals, usually in a hospital setting. It is not suitable for everyone, and there are important risks and benefits to consider. Close monitoring is required during and after administration.

Frequently Asked Questions about Streptokinase

What is streptokinase used for?

Streptokinase is used to dissolve blood clots in conditions such as heart attack (acute myocardial infarction), pulmonary embolism, and deep vein thrombosis.

How does streptokinase work?

It activates plasminogen to plasmin, which breaks down fibrin in blood clots, helping to dissolve them and restore blood flow.

What are the most common side effects?

Common side effects include mild fever, chills, nausea, headache, and mild bleeding or bruising at the injection site.

Who should not receive streptokinase?

People with active internal bleeding, recent stroke, recent major surgery, severe hypertension, or known allergy to streptokinase should not receive this medication.

Can streptokinase be given more than once?

Repeated use is generally avoided due to the risk of allergic reactions and reduced effectiveness from antibody formation.

Is streptokinase safe during pregnancy?

Streptokinase should only be used during pregnancy if the potential benefit justifies the risk. Discuss with your healthcare provider.

What should I do if I experience severe bleeding after streptokinase?

Seek immediate medical attention. Severe bleeding is a medical emergency and requires prompt intervention.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.