Rasagiline (rasagiline) — Uses, Dosage, Side Effects & Safety

Drug class: Monoamine Oxidase Type B (MAO-B) Inhibitor; Antiparkinsonian agent

Overview

Rasagiline is a prescription medication used to treat symptoms of Parkinson’s disease, such as muscle stiffness, tremors, and difficulty with movement. It is often used alone in early Parkinson’s or in combination with other medications, like levodopa, in more advanced stages. Rasagiline works by increasing the levels of dopamine, a natural substance in the brain that helps control movement. It does this by blocking an enzyme called monoamine oxidase type B (MAO-B), which breaks down dopamine. Key points for patients: Rasagiline does not cure Parkinson’s disease but can help improve symptoms and quality of life. It is important to take this medication exactly as prescribed and to be aware of potential side effects and drug interactions.

Therapeutic uses

  • Parkinson's disease (monotherapy in early-stage)
  • Parkinson's disease (adjunctive therapy with levodopa in fluctuating patients)
  • Improvement of motor symptoms in Parkinson's disease

Common side effects

  • Dyskinesia
  • Headache
  • Nausea
  • Orthostatic hypotension
  • Falls
  • Hallucinations
  • Serotonin syndrome

Frequently Asked Questions about Rasagiline

What is rasagiline used for?

Rasagiline is used to treat symptoms of Parkinson’s disease, such as tremors, stiffness, and movement difficulties. It can be used alone or with other medications like levodopa.

How does rasagiline work?

Rasagiline works by blocking the MAO-B enzyme, which breaks down dopamine in the brain. This increases dopamine levels, helping to improve movement and reduce symptoms of Parkinson’s disease.

Can I take rasagiline with other Parkinson’s medications?

Yes, rasagiline is often used with other Parkinson’s medications, especially levodopa. However, your doctor will monitor for side effects and adjust doses as needed.

What foods should I avoid while taking rasagiline?

You should avoid consuming large amounts of foods very high in tyramine, such as aged cheeses, cured meats, and some fermented products, as they may raise blood pressure.

What are the most common side effects of rasagiline?

Common side effects include headache, joint pain, indigestion, nausea, and mild dizziness. Serious side effects are rare but require immediate medical attention.

Is rasagiline safe during pregnancy or breastfeeding?

There is limited information on the safety of rasagiline during pregnancy or breastfeeding. It should only be used if clearly needed and prescribed by your doctor.

What should I do if I miss a dose?

Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double up doses.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.