Oxacillin (Oxacillin sodium) — Uses, Dosage, Side Effects & Safety

Drug class: Antibiotic (Penicillinase-resistant penicillin)

Overview

Oxacillin is an antibiotic used to treat infections caused by certain bacteria, especially those resistant to other penicillins. It is commonly prescribed for skin, bone, joint, and bloodstream infections, as well as pneumonia and endocarditis caused by susceptible staphylococci. Oxacillin works by stopping the growth of bacteria. It belongs to the penicillin group of antibiotics and is specifically designed to resist breakdown by bacterial enzymes (beta-lactamases) that make other penicillins ineffective. Patients should complete the full course of oxacillin, even if they feel better, to ensure the infection is fully treated and to reduce the risk of antibiotic resistance. It is important to use this medication only for bacterial infections as it will not work for viral illnesses like the common cold.

Frequently Asked Questions about Oxacillin

What infections does oxacillin treat?

Oxacillin is used to treat infections caused by penicillinase-producing staphylococci, including skin, bone, joint, bloodstream, and respiratory infections.

Can I take oxacillin if I am allergic to penicillin?

No, you should not take oxacillin if you have a known allergy to penicillins. Inform your doctor about any antibiotic allergies.

Is oxacillin safe during pregnancy and breastfeeding?

Oxacillin is generally considered safe during pregnancy and breastfeeding, but should only be used if clearly needed and prescribed by your doctor.

What should I do if I develop diarrhea while taking oxacillin?

Contact your healthcare provider if you develop severe or persistent diarrhea, as this may indicate a serious intestinal infection.

How long does it take for oxacillin to work?

Improvement is usually seen within a few days, but the full course should be completed as prescribed to ensure the infection is fully treated.

Can oxacillin be given orally?

Oxacillin is primarily administered by injection. Oral forms are not widely available or used.

Does oxacillin interact with other medications?

Yes, oxacillin can interact with methotrexate, oral contraceptives, and some anticoagulants. Always inform your healthcare provider about all medications you are taking.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.