Kerendia (Finerenone) (Finerenone) — Uses, Dosage, Side Effects & Safety

Drug class: Non-steroidal mineralocorticoid receptor antagonist (MRA)

Overview

Kerendia (Finerenone) is a prescription medication used to treat adults with chronic kidney disease (CKD) associated with type 2 diabetes. It helps slow the progression of kidney damage and reduces the risk of cardiovascular complications, such as heart attack and hospitalization for heart failure. Finerenone works by blocking the effects of the hormone aldosterone, which can cause inflammation and scarring in the kidneys and heart. By reducing these harmful effects, Kerendia helps protect kidney function and the cardiovascular system. Key points for patients: Take Kerendia exactly as prescribed, usually once daily with or without food. Regular blood tests are needed to monitor potassium and kidney function. Do not use Kerendia if you have high potassium levels or severe kidney impairment.

Therapeutic uses

  • To reduce the risk of sustained eGFR decline
  • To reduce the risk of end-stage kidney disease
  • To reduce the risk of cardiovascular death
  • To reduce the risk of non-fatal myocardial infarction
  • To reduce the risk of hospitalization for heart failure

Common side effects

  • Hyperkalemia
  • Hypotension
  • Hyponatremia
  • Increased serum creatinine
  • Anemia
  • Urinary tract infection

Frequently Asked Questions about Kerendia (Finerenone)

What is Kerendia (Finerenone) used for?

Kerendia is used to reduce the risk of kidney and heart complications in adults with chronic kidney disease (CKD) associated with type 2 diabetes.

How does Kerendia work?

Kerendia blocks the effects of aldosterone, a hormone that can cause inflammation and scarring in the kidneys and heart, helping to protect these organs.

What are the most common side effects?

The most common side effects are increased potassium levels (hyperkalemia), mild dizziness, and low blood pressure.

Can I take Kerendia with other diabetes or blood pressure medications?

Yes, but your doctor will monitor for interactions, especially with medications that affect potassium levels or kidney function.

What should I do if I miss a dose?

Take the missed dose as soon as you remember on the same day. If it is almost time for your next dose, skip the missed dose and continue your regular schedule.

Is Kerendia safe during pregnancy or breastfeeding?

Kerendia is not recommended during pregnancy or breastfeeding due to potential risks to the fetus or infant.

How often do I need blood tests while taking Kerendia?

Your doctor will check your potassium and kidney function before starting Kerendia, within 4 weeks of starting, and regularly thereafter.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.