Jynneos (Smallpox/Monkeypox vaccine) (Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN)) — Uses, Dosage, Side Effects & Safety

Drug class: Vaccine (Live, Non-replicating)

Overview

Jynneos is a vaccine used to help protect adults against smallpox and monkeypox. It is a non-replicating live vaccine, meaning it contains a weakened virus that cannot reproduce in the body, making it safer for people with weakened immune systems. Jynneos works by stimulating your immune system to produce antibodies and immune cells that can recognize and fight the viruses that cause smallpox and monkeypox. It does not contain the actual smallpox or monkeypox viruses, so it cannot cause these diseases. Key points: Jynneos is given as two injections, 4 weeks apart. It is recommended for people at high risk of exposure, such as laboratory workers, healthcare workers, and those identified during outbreaks. It is generally well-tolerated and can be used in people with weakened immune systems or skin conditions like eczema.

Frequently Asked Questions about Jynneos (Smallpox/Monkeypox vaccine)

What does Jynneos protect against?

Jynneos protects against smallpox and monkeypox by helping your immune system recognize and fight these viruses.

Who should get the Jynneos vaccine?

It is recommended for adults at high risk of exposure to smallpox or monkeypox, such as laboratory workers, healthcare workers, and those identified during outbreaks.

Can Jynneos cause smallpox or monkeypox?

No. Jynneos contains a non-replicating virus that cannot cause smallpox or monkeypox.

How many doses of Jynneos are needed?

Two doses, given 4 weeks apart, are needed for full protection.

Is Jynneos safe for people with weakened immune systems?

Yes, Jynneos is considered safe for people with weakened immune systems because it does not contain a replicating virus.

What should I do if I miss my second dose?

Contact your healthcare provider to reschedule. The second dose should be given as soon as possible; you do not need to restart the series.

Are there any long-term side effects?

Long-term side effects are rare. Most side effects are mild and temporary. Serious reactions are very uncommon.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.