Glycopyrronium/Indacaterol (Ultibro Breezhaler) (glycopyrronium bromide and indacaterol maleate) — Uses, Dosage, Side Effects & Safety

Drug class: Long-acting muscarinic antagonist (LAMA) and long-acting beta2-agonist (LABA) combination

Overview

Glycopyrronium/Indacaterol (Ultibro Breezhaler) is a combination inhaler used to treat adults with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It helps to relax and open the airways, making it easier to breathe and reducing symptoms like shortness of breath, cough, and wheezing. This medication contains two active ingredients: glycopyrronium, which blocks certain receptors in the lungs to prevent airway tightening, and indacaterol, which relaxes the muscles around the airways. Together, they provide long-lasting bronchodilation for improved lung function. Key points for patients: This inhaler is not a rescue medicine and should not be used for sudden breathing problems. It is taken once daily at the same time each day. Always use the inhaler device as instructed and do not swallow the capsules.

Therapeutic uses

  • Chronic obstructive pulmonary disease (COPD)
  • Bronchospasm associated with COPD
  • Maintenance treatment of airflow obstruction in COPD

For related Glycopyrronium/Indacaterol (Ultibro Breezhaler) guidance, compare Emphysema(COPD): Symptoms, Causes, and Treatment and COPD: Symptoms, Causes, Diagnosis, and Treatment.

Common side effects

  • Headache
  • Nasopharyngitis
  • Cough
  • Urinary tract infection
  • Muscle spasms
  • Palpitations
  • Paradoxical bronchospasm

Frequently Asked Questions about Glycopyrronium/Indacaterol (Ultibro Breezhaler)

What is Glycopyrronium/Indacaterol (Ultibro Breezhaler) used for?

It is used for long-term maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema, to help improve breathing and reduce symptoms.

How should I use the Ultibro Breezhaler device?

Insert one capsule into the Breezhaler device, pierce the capsule, and inhale the powder deeply. Do not swallow the capsule. Follow the instructions provided with your inhaler.

Can I use this inhaler for sudden breathing problems?

No, Glycopyrronium/Indacaterol is not a rescue inhaler. It should not be used for acute symptoms or sudden breathing attacks. Use a fast-acting inhaler as prescribed for emergencies.

What should I do if I miss a dose?

Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not take two doses at once.

Are there any foods or medicines I should avoid?

Avoid using other inhaled bronchodilators or anticholinergic medications unless directed by your doctor. Inform your healthcare provider about all medicines and supplements you take.

What are the most common side effects?

Common side effects include sore throat, cough, headache, dry mouth, and mild muscle cramps. Serious side effects are rare but require immediate medical attention.

Is it safe to use during pregnancy or breastfeeding?

There is limited data on use in pregnancy or breastfeeding. Discuss with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.