Fludrocortisone (Fludrocortisone acetate) — Uses, Dosage, Side Effects & Safety
Drug class: Corticosteroid (Mineralocorticoid)
Overview
Fludrocortisone is a prescription medication used to treat conditions where your body does not produce enough of its own natural steroids, especially aldosterone. It is most commonly prescribed for Addison’s disease (adrenal insufficiency) and for certain types of salt-losing adrenogenital syndrome. Fludrocortisone works by helping your body retain sodium and excrete potassium, which helps maintain proper blood pressure and salt balance. This is important for preventing dehydration and low blood pressure in people whose adrenal glands are not functioning properly. Key points for patients: Take fludrocortisone exactly as prescribed, usually once daily. Do not stop taking it suddenly without your doctor’s advice. You may need regular blood tests to monitor your body’s salt and potassium levels.
Therapeutic uses
- Adrenocortical insufficiency (Addison's disease)
- Salt-losing adrenogenital syndrome
- Orthostatic hypotension (neurogenic)
Common side effects
- Edema
- Hypertension
- Hypokalemia
- Muscle weakness
- Mood changes
- Weight gain
- Hyperglycemia
Frequently Asked Questions about Fludrocortisone
What is fludrocortisone used for?
Fludrocortisone is mainly used to treat Addison’s disease and certain salt-losing forms of adrenogenital syndrome. It helps your body retain sodium and maintain blood pressure.
How should I take fludrocortisone?
Take fludrocortisone exactly as prescribed, usually once daily, at the same time each day. Swallow the tablet whole with water.
What should I do if I miss a dose?
Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double the dose.
What are the serious side effects of fludrocortisone?
Serious side effects include severe swelling, high blood pressure, muscle weakness, irregular heartbeat, and signs of infection. Seek medical attention if these occur.
Can I stop taking fludrocortisone suddenly?
No, do not stop fludrocortisone suddenly without your doctor’s advice, as this can cause adrenal crisis.
Are there any foods or medicines I should avoid?
Avoid high-sodium foods unless advised, and inform your doctor about all other medicines you take, as interactions are possible.
Is fludrocortisone safe during pregnancy or breastfeeding?
Discuss with your doctor. Fludrocortisone may be used if the benefits outweigh the risks, but close monitoring is required.
Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.