Erenumab (erenumab) — Uses, Dosage, Side Effects & Safety

Drug class: Calcitonin Gene-Related Peptide (CGRP) Receptor Antagonist; Monoclonal Antibody

Overview

Erenumab is a prescription medicine used to prevent migraine headaches in adults. It belongs to a class of drugs called CGRP receptor antagonists, which work by blocking the activity of a molecule involved in migraine attacks. Erenumab is given as a once-monthly injection under the skin. It is not used to treat a migraine attack that has already started, but rather to reduce the number and severity of migraine days over time. Patients should know that it may take several weeks to notice the full benefits. Erenumab is generally well tolerated, but some people may experience side effects such as injection site reactions or constipation.

Therapeutic uses

  • Migraine prevention

For related Erenumab guidance, compare Migraines: Symptoms, Causes, Diagnosis, and Treatment.

Common side effects

  • Constipation
  • Injection site reactions
  • Muscle cramps
  • Back pain
  • Hypersensitivity reactions
  • Hypertension
  • Angioedema

Frequently Asked Questions about Erenumab

How long does it take for erenumab to start working?

Some people may notice fewer migraine days within the first month, but it can take up to 3 months to see the full benefit of erenumab.

Can I use erenumab to treat a migraine attack?

No, erenumab is not for acute migraine attacks. It is used to prevent migraines from occurring.

What should I do if I experience severe constipation while taking erenumab?

Contact your healthcare provider immediately if you develop severe constipation, especially if it is associated with abdominal pain or vomiting.

Is erenumab safe during pregnancy or breastfeeding?

There is limited data on the safety of erenumab in pregnancy or breastfeeding. Discuss risks and benefits with your doctor before use.

Can I self-inject erenumab at home?

Yes, after proper training by your healthcare provider, you can self-inject erenumab at home using a pre-filled syringe or autoinjector.

Does erenumab interact with other migraine medications?

Erenumab is not known to interact with most other migraine medications, but always inform your doctor about all medicines you use.

What should I do if I miss a dose of erenumab?

Take the missed dose as soon as you remember, then continue with your next dose in one month. Do not double up doses.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.