Cyclosporine (cyclosporine) — Uses, Dosage, Side Effects & Safety

Drug class: Immunosuppressant (Calcineurin Inhibitor)

Overview

Cyclosporine is a prescription medicine used to prevent organ rejection in people who have received kidney, liver, or heart transplants. It is also used to treat certain autoimmune conditions, such as severe rheumatoid arthritis and psoriasis, and as an eye drop for chronic dry eye disease. Cyclosporine works by suppressing the immune system to prevent it from attacking transplanted organs or the body's own tissues. By lowering immune activity, it helps reduce inflammation and the risk of organ rejection. Key points for patients: Cyclosporine requires regular blood tests to monitor drug levels and kidney function. It can increase the risk of infections and certain cancers. Always take it exactly as prescribed and do not stop suddenly without consulting your doctor.

Therapeutic uses

  • Organ transplantation
  • Autoimmune diseases

For related Cyclosporine guidance, compare Tacrolimus.

Common side effects

  • Nephrotoxicity
  • Hypertension
  • Hirsutism
  • Gingival hyperplasia
  • Tremor
  • Increased risk of infections
  • Increased risk of malignancy

Frequently Asked Questions about Cyclosporine

What is cyclosporine used for?

Cyclosporine is used to prevent organ rejection after kidney, liver, or heart transplantation, and to treat autoimmune conditions such as severe rheumatoid arthritis, psoriasis, and chronic dry eye disease.

How does cyclosporine work?

Cyclosporine suppresses the immune system by inhibiting the activity of T-cells, which helps prevent the body from attacking transplanted organs or its own tissues.

What are the most common side effects?

Common side effects include increased hair growth, tremor, headache, high blood pressure, and gum swelling.

Can I take cyclosporine with other medications?

Cyclosporine interacts with many medications, including some antibiotics, antifungals, and herbal supplements. Always check with your healthcare provider before starting new medicines.

How is cyclosporine monitored?

Regular blood tests are required to monitor cyclosporine levels, kidney and liver function, and blood pressure.

Is it safe during pregnancy or breastfeeding?

Cyclosporine should only be used during pregnancy or breastfeeding if clearly needed and prescribed by your doctor, as it may pose risks to the baby.

What should I do if I miss a dose?

Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double up doses.

Educational information only. Always consult a qualified healthcare professional before starting, stopping, or changing any medication.