Docusate

Colace (docusate) is a stool softener used to treat or prevent occasional constipation. Docusate is used for Constipation.

Also called: Prolaxa (United States) · Dioctyl (United Kingdom) · Soflax (Canada) · Waxsol (Australia) · Otowax (Philippines)

Pronunciation: (koh-LACE, DOCK-yoo-sate).

Generic name: docusate
Brand names: Doc-Q-Lace, Diocto, Laxsol, Soflax, Docusol, Surfak
Drug class: Stool softener (laxative)

Availability and supply rules vary by country

Trade names by country: United States · United Kingdom · Canada · Australia · India · New Zealand

Australia: Waxsol, Coloxyl · Full directory

What docusate is and how it works

Colace (docusate) is a stool softener used to treat or prevent occasional constipation. It works by increasing the amount of water the stool absorbs in the gut, making the stool softer and easier to pass. This can help reduce straining during bowel movements, which is especially important for people recovering from surgery, childbirth, or those with hemorrhoids. Colace does not stimulate the bowel directly, so it is generally gentle and less likely to cause cramping compared to stimulant laxatives. It is usually effective within 12 to 72 hours after taking a dose. Patients should use Colace only as directed and not for longer than one week unless advised by a healthcare provider. (2)

Uses, formulations, monitoring, and supply rules can differ by patient, product, and country. Follow the exact local product information and professional advice.

Mechanism of action: how docusate works

Docusate is an anionic surfactant that lowers the surface tension of stool, allowing water and lipids to penetrate and soften fecal material. This facilitates easier defecation without stimulating intestinal peristalsis. (1)

What is Docusate used for?

Constipation

Constipation (2)

Before taking docusate

Do not take / not appropriate for

Contraindicated in patients with known hypersensitivity to docusate, intestinal obstruction, acute abdominal pain of unknown origin, or undiagnosed rectal bleeding. (Contraindication) (2)

Tell your clinician about

(2)

Docusate dosage and how to take it

General Instructions: Take Colace exactly as directed on the package or by your healthcare provider. Do not take larger or smaller amounts or for longer than recommended.. Adult Dosing: Usual dose: 50–300 mg daily in single or divided doses. Dose may be adjusted based on response.. Pediatric Dosing: Children 2–12 years: 50–150 mg daily in divided doses. Children under 2 years: Use only under medical supervision.. Administration: Take with a full glass of water. Capsules and tablets should be swallowed whole. Liquid forms may be mixed with milk or juice to mask the taste.. When To Stop: If you have no bowel movement after using Colace for 7 days, or if you develop rectal bleeding or severe abdominal pain, seek medical advice promptly; let the clinician you see advise on whether to continue or stop use.. Storage: Store at room temperature, away from moisture and heat. Keep out of reach of children.
This page does not provide a dose calculator. Dosing must follow the prescriber, pharmacist, or product label.

(2)

Procedures and treatment changes

Tell the treating team before surgery, procedures, or any medicine change. Do not alter treatment without the responsible clinician. (2)

Missed dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not take two doses at the same time.

Overdose

Symptoms of overdose may include nausea, vomiting, stomach cramps, or diarrhea. Seek emergency medical attention immediately or contact a poison control center (in the US, Poison Help: 1-800-222-1222). (2)

Docusate side effects

Side effects and their urgency vary; report severe, persistent, or concerning symptoms to a healthcare professional.