Albuterol

Pronunciation: al-BYOO-ter-ol.

Generic name
albuterol (the US adopted name for salbutamol)
Brand names
ProAir HFA (United States), Ventolin HFA (United States, Canada)
Drug class
Short-acting beta-2 agonist (SABA) bronchodilator
Form
Metered-dose inhaler (90 mcg per actuation)
Route
Oral inhalation
Legal status
Prescription-only

Availability and supply rules vary by country

Trade names by country: United States · United Kingdom · Canada · Australia · New Zealand

Australia: Ventolin (salbutamol) (5) · Full directory

What albuterol (the US adopted name for salbutamol) is and how it works

Albuterol is a prescription-only quick-relief (rescue) inhaler used to treat or prevent sudden breathing difficulty (bronchospasm) caused by asthma or other reversible airway conditions. It works within minutes and its effect lasts around 4-6 hours. (1)

Use your albuterol inhaler exactly as your prescriber directs for quick relief of wheezing, coughing, or shortness of breath. If you find you need it more and more often, this is a real warning sign that your asthma is not well controlled and needs a review with your prescriber -- it is not something to manage by increasing your own dose or changing your other medicines yourself.

Mechanism of action: how albuterol (the US adopted name for salbutamol) works

Albuterol is a selective beta-2 adrenergic receptor agonist that relaxes bronchial smooth muscle, producing bronchodilation within minutes with an effect lasting approximately 4-6 hours. (1)

What albuterol (the US adopted name for salbutamol) is used for

Quick relief of bronchospasm

Used to treat or prevent sudden narrowing of the airways (bronchospasm) in people aged 4 and older with asthma or other reversible airway disease. (1)

Prevention of exercise-induced bronchospasm

Used shortly before exercise to help prevent breathing difficulty triggered by physical activity, in people aged 4 and older. (1)

Before taking albuterol (the US adopted name for salbutamol)

Do not take / not appropriate for

  • Do not use albuterol if you have had a hypersensitivity reaction to albuterol or any component of the inhaler. (all countries) (1)

Tell your clinician about

  • Any heart conditions, including coronary artery disease, irregular heartbeat, or high blood pressure.
  • Any history of seizures or diabetes.
  • Any history of low potassium levels.
  • All other medicines you use, especially other inhalers, beta-blockers, diuretics ('water tablets'), or antidepressants.
  • Pregnancy, plans for pregnancy, or breastfeeding.
  • How often you are using your rescue inhaler -- needing it more often than usual is important information for your prescriber, not something to manage on your own.
(1)

How to take albuterol (the US adopted name for salbutamol)

  • Use exactly as prescribed, shaking the inhaler well before each use and using the correct inhaler technique your prescriber or pharmacist showed you.
  • This is a rescue/reliever inhaler for quick relief of symptoms, or to prevent symptoms shortly before exercise -- it is not meant to be your main, ongoing asthma treatment.
  • If you notice you are using your rescue inhaler more often than your prescriber advised, contact your prescriber for a review of your asthma control -- this is a real sign your asthma treatment plan may need adjusting.
  • If your breathing suddenly gets worse right after using this inhaler, this can be a rare but serious reaction to the inhaler itself (paradoxical bronchospasm) -- seek emergency medical help immediately.
(1)

Procedures and treatment changes

Tell the treating team before surgery, procedures, or any medicine change. Do not alter treatment without the responsible clinician. (1) (3) (2) (4) (5) (6)

Missed dose

Albuterol is generally used as needed for symptoms or before exercise rather than on a fixed schedule, so a 'missed dose' does not usually apply in the way it does for regular daily medicines. If you use albuterol on a scheduled basis for any reason, ask your prescriber or pharmacist for specific guidance.

Overdose

Seek emergency medical help immediately if an overdose is suspected. Reported effects of excessive use include chest pain, a fast or irregular heartbeat, tremor, and seizures; fatalities have been reported with excessive use of inhaled bronchodilators like albuterol. (1)

Side effects

Side effects and their urgency vary; report severe, persistent, or concerning symptoms.

Fast heartbeat (tachycardia).

What to notice: Fast heartbeat (tachycardia).

What to do: Discuss persistent or troublesome symptoms with the treating clinician or pharmacist. (1)

Tremor (shakiness).

What to notice: Tremor (shakiness).

What to do: Discuss persistent or troublesome symptoms with the treating clinician or pharmacist. (1)

Headache.

What to notice: Headache.

What to do: Discuss persistent or troublesome symptoms with the treating clinician or pharmacist. (1)

Dizziness, or throat/nose irritation.

What to notice: Dizziness, or throat/nose irritation.

What to do: Discuss persistent or troublesome symptoms with the treating clinician or pharmacist. (1)

Serious warnings

Sudden worsening of breathing right after using the inhaler (paradoxical bronchospasm) — emergency

Symptoms: Wheezing or breathing difficulty that suddenly gets worse immediately after a dose, rather than better.

Action: Seek emergency medical help immediately. This is a rare but serious reaction to the inhaler itself; a clinician will assess and decide on further treatment. (1) (2)

Increasing need for this rescue inhaler — high caution

Symptoms: Needing your rescue inhaler more often than your prescriber advised, or more than roughly twice a week for symptom relief outside of exercise use.

Action: Contact your prescriber for a review -- this is a genuine warning sign of worsening or poorly controlled asthma that needs a change in your overall treatment plan, decided by your prescriber, not a signal to increase your own dose or adjust other medicines yourself. (2) (1)

Cardiovascular symptoms — high caution

Symptoms: Chest pain, a fast or irregular heartbeat, or palpitations, especially in people with existing heart disease.

Action: Seek emergency medical help immediately for chest pain or a very irregular heartbeat; tell your prescriber about any heart conditions before starting. (2) (1)

Signs of a serious allergic reaction — emergency

Symptoms: Swelling of the face, lips, tongue, or throat; difficulty breathing; widespread rash or hives.

Action: Seek emergency medical help immediately. (1)

Interactions

  • Other sympathomimetic aerosol bronchodilators should generally not be used at the same time as albuterol. (1)
  • Beta-blocker medicines can reduce albuterol's effect and, in susceptible patients, may cause severe bronchospasm. (1) (2)
  • Diuretics ('water tablets') and steroid medicines can add to the risk of low potassium (hypokalemia) from albuterol. (1) (2)
  • MAOIs and tricyclic antidepressants can increase albuterol's cardiovascular effects. (1)

Pregnancy, breastfeeding, kidney/liver function, age

Pregnancy

Use only if the potential benefit justifies the potential risk to the fetus, as assessed by your prescriber; a related salbutamol source notes safety in pregnancy has not been formally established. (1) (3) (2) (4) (5) (6)

Breastfeeding

It is not known whether albuterol passes into human milk in clinically significant amounts; use caution and discuss with your prescriber. (1) (3) (2) (4) (5) (6)

Children

Approved for bronchospasm treatment and exercise-induced bronchospasm prevention from age 4. (1) (3) (2) (4) (5) (6)

Elderly

No specific dose adjustment based on age alone is described in the source reviewed, though cardiovascular caution applies broadly to older patients with heart disease. (1) (3) (2) (4) (5) (6)

Hepatic_impairment

Not specifically detailed in the source reviewed. (1) (3) (2) (4) (5) (6)

Source_ids

US-DAILYMED-ALBUTEROL-2026,UK-EMC-SALBUTAMOL-VENTOLIN-2026 (1) (3) (2) (4) (5) (6)

Monitoring

Before starting

  • Baseline asthma control assessment
  • Cardiovascular history review
  • Inhaler technique check

During treatment

  • Track how often you use your rescue inhaler -- increasing use is a signal for prescriber review, not self-management.
  • Watch for cardiovascular symptoms (chest pain, palpitations) and for paradoxical worsening of breathing right after a dose.
  • Periodic asthma control review with your prescriber.
(1) (2)

Storage

Store between 15-25°C (59-77°F). Do not puncture, break, or burn the canister, even when it appears empty.

Professional information

Clinician-facing context only, sourced from the current US FDA prescribing information; verify against the current full label before prescribing.

United States

Indication: Bronchospasm (treatment/prevention) and exercise-induced bronchospasm prevention

Dose summary: 2 inhalations every 4-6 hours as needed for bronchospasm (or 1 inhalation every 4 hours); 2 inhalations 15-30 minutes before exercise. Approved from age 4. Increasing need for doses signals inadequate asthma control requiring reassessment of the overall treatment regimen.

Renal context: Not specifically detailed in the source reviewed. (1)

Mechanism of action

Hepatic guidance

Not specifically detailed in the source reviewed.

Overdose note

Reported overdose effects include exaggerated beta-agonist effects: tachycardia, tremor, chest pain, hypokalemia, and seizures; fatalities have been reported with excessive inhaled sympathomimetic use. Manage supportively, including cardiac monitoring and correction of hypokalemia as needed. (1)

Frequently asked questions

What should I do if my breathing suddenly gets worse right after using my albuterol inhaler?

This can be a rare but serious reaction called paradoxical bronchospasm, where the inhaler itself appears to worsen breathing instead of relieving it. Seek emergency medical help immediately -- this is a real medical emergency, and a clinician will decide on further treatment. (1) (2)

I'm using my rescue inhaler a lot more than I used to -- is that a problem?

Yes. Needing your rescue inhaler more often is a genuine warning sign that your asthma is not well controlled, and it needs a review with your prescriber to adjust your overall treatment plan. It is not something to manage by taking more of this inhaler on your own or changing your other medicines yourself. (2) (1)

Is albuterol the same medicine as salbutamol?

Yes. Albuterol and salbutamol are the same active medicine -- albuterol is the name used in the United States, while salbutamol is the name used internationally, including in the UK, EU, Canada, Australia, and New Zealand. (1) (2)

What is the mechanism of action of albuterol (the US adopted name for salbutamol)?

Albuterol is a selective beta-2 adrenergic receptor agonist that relaxes bronchial smooth muscle, producing bronchodilation within minutes with an effect lasting approximately 4-6 hours. (1)

What is the generic name of Albuterol?

The generic name is albuterol (the US adopted name for salbutamol). It is sold under brand names including ProAir HFA (United States), Ventolin HFA (United States, Canada). (1)

What class of drug is albuterol (the US adopted name for salbutamol)?

Albuterol is classed as: Short-acting beta-2 agonist (SABA) bronchodilator. (1)

References

  1. PROAIR HFA (albuterol sulfate) inhalation aerosol -- full prescribing informationU.S. Food and Drug Administration / DailyMed (NIH), full prescribing information, Teva (ProAir HFA) · United States · accessed 2026-07-29 · source 1
  2. Ventolin Evohaler 100 micrograms -- Summary of Product Characteristicselectronic medicines compendium (emc), United Kingdom -- GSK · United Kingdom · accessed 2026-07-29 · source 2
  3. Levosalbutamol, salbutamol -- list of nationally authorised medicinal products / PSUSA single assessmentEuropean Medicines Agency (EMA) -- salbutamol is nationally authorised across EU member states via national procedures · European Union · accessed 2026-07-29 · source 3
  4. Ventolin HFA (salbutamol) Product MonographHealth Canada product monograph · Canada · accessed 2026-07-29 · source 4
  5. Ventolin (salbutamol) -- ARTG registrationsTherapeutic Goods Administration (TGA), Australia · Australia · accessed 2026-07-29 · source 5
  6. Ventolin (salbutamol) New Zealand Data SheetsMedsafe (New Zealand regulator) · New Zealand · accessed 2026-07-29 · source 6

Brand names by country

Single-ingredient albuterol (the US adopted name for salbutamol) names are shown separately by country. Product availability, strengths, and supply rules can change; combination products are not included here.

Priority countries

United States

  • VENTOLIN HFA90 ug · glaxosmithkline llc
  • Albuterol Sulate HFA90 ug · nucare pharmaceuticals,inc.
  • ProAir Digihaler90 ug · teva respiratory, llc

United Kingdom

  • Ventolin Evohaler (salbutamol) (2)MHRA licensed emc smpc confirmed · 100 mcg per actuation · GlaxoSmithKline

Canada

  • Ventolin HFA (salbutamol) (4)Health Canada approved confirmed · 100 mcg per actuation · GSK Canada

Australia

  • Ventolin (salbutamol) (5)TGA ARTG registered confirmed · 100 mcg per actuation · GlaxoSmithKline Australia Pty Ltd

New Zealand

  • Ventolin (salbutamol) (6)Medsafe approved confirmed · 100 mcg per actuation · GSK New Zealand
View brands in additional countries.

European Union

Ventoline (salbutamol) (3)

This page provides general reference information about albuterol and is not a substitute for advice from the prescriber managing your treatment. All dosing and treatment decisions should be made with your prescriber.

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