Ferritin Blood Test

Reviewed

Also called: Serum ferritin, Ferritin level, Ferritin serum

Ferritin is an iron-storage protein; a blood ferritin result helps assess iron stores but also changes with inflammation and illness.

Specimen: Blood

Why this test may be ordered

  • Investigating possible iron deficiency or overload
  • Assessing anaemia with other tests
  • Monitoring an iron-related condition or treatment

Preparation and collection

Follow the laboratory's instructions about fasting and collection time; requirements differ when ferritin is ordered with other iron studies. Report iron supplements and medicines, and do not stop them unless instructed.

A health professional usually takes a small blood sample from a vein. Collection normally takes only a few minutes.

Blood collection has a small risk of brief discomfort, bruising, light-headedness, or rarely infection at the needle site.

Understanding results

Ferritin should be interpreted with the laboratory interval, symptoms, CBC, other iron studies, inflammation, liver health, age, sex, and pregnancy status.

  • Low ferritin: A low result can indicate depleted iron stores or iron deficiency. Limitation: Severity and cause require clinical assessment; ferritin is only part of the investigation. Next step: Discuss the result with the clinician and assess CBC, iron intake, blood loss, absorption, pregnancy, and the need for treatment or further investigation.
  • High ferritin: A high result can occur with inflammation, infection, liver disease, metabolic conditions, cancer, or iron overload. Limitation: High ferritin does not by itself prove excess body iron. Next step: Discuss the result with the clinician and review other iron studies, inflammation markers, liver tests, history, and repeat or specialist testing when indicated.
  • Inflammation, infection, liver disease, and some cancers can raise ferritin, so a result that is not low does not always exclude iron deficiency.
  • Laboratory intervals vary and pregnancy or chronic disease changes interpretation.

What to do next

Follow-up may include CBC, transferrin saturation, serum iron/TIBC, inflammation markers, liver tests, or investigation for blood loss.

  • Which reference interval and units apply to my result?
  • Could medicines, supplements, illness, or sample timing affect this result?
  • Do I need a repeat test or another test before any conclusion is made?

Evidence source

U.S. National Library of Medicine: Ferritin Blood Test

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