Alpha-fetoprotein (AFP) tumor marker test
Reviewed
An AFP tumor marker test is a blood test that measures the level of alpha-fetoprotein (AFP) to help monitor certain cancers (liver, ovarian, testicular germ cell) and chronic liver disease. It is not used alone to screen for or diagnose cancer. Results must be interpreted by a healthcare professional.
Preparation and collection
No special preparations needed.
Understanding this test
Use the reference interval and units printed by the laboratory that performed the test. A result outside that interval is not a diagnosis by itself, and a result inside it does not rule out every condition. Your symptoms, history, medicines, timing, and related tests can change what the result means.
- High AFP levels may also be caused by noncancerous conditions such as cirrhosis, chronic hepatitis B or C, or liver disease.
- Some people with liver, ovarian, or testicular cancer can have normal AFP levels.
- This test alone cannot be used to screen for or diagnose cancer.
What to do next
Ask your provider to explain what your test results mean for your health.
Evidence source
U.S. National Library of Medicine: Alpha-fetoprotein (AFP) tumor marker test